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ea0032p965 | Pituitary – Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2013

Central hypothyroidism and adjusted thyroxine dose study (CHATS): impact of increasing free thyroxine levels in patients with hypopituitarism

Minder Anna-Elisabeth H , Jostel Andreas , Higham Claire E , Ryder W David J , Trainer Peter J , Shalet Stephen M

Introduction: Patients with pituitary deficiencies suffer from impaired quality of life regardless of substitution therapy with hydrocortisone, thyroxine (T4), sex hormones or GH. Central hypothyroidism (CH) is difficult to diagnose and treat because symptoms are non-specific and TSH-levels cannot be used for assessment. There is no consensus for the fT4-goal of thyroxine-replacement in patients with CH.Aim: To determine the impact ...

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Central hypothyroidism and adjusted thyroxine dose study (CHATS): impact of increasing free thyroxine levels in patients with hypopituitarism

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